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Domestic futures opened mixed at night, with Shanghai Gold down 0.57%, Shanghai Silver down more than 1%, Shanghai Zinc up 0.68%, thread down 0.5%, coking coal down 0.6%, glass down 1.22% and crude oil up nearly 1%.COMEX silver fell 2.00% in the day and is now quoted at $30.99 per ounce. COMEX silver fell to $31 per ounce, down 1.97% in the day.Kexing launched the world's first phase III clinical study of bivalent inactivated enterovirus vaccine. On December 13th, the first volunteer was enrolled in the phase III clinical study of bivalent inactivated enterovirus vaccine developed by Beijing Kexing Biological Products Co., Ltd., a subsidiary of Kexing Holding Biotechnology Co., Ltd. (hereinafter referred to as "Kexing"). The vaccine is used to prevent hand, foot and mouth disease caused by enterovirus 71 (EV71) and coxsackie virus 16 (CA16). A multicenter, randomized, double-blind, controlled study design was adopted in this phase III clinical study to evaluate the protective efficacy, safety and immunogenicity of the vaccine in children aged 6-71 months.

Kang Enbei: Amikacin Sulfate Injection is planned to win the bid for the tenth batch of national centralized drug purchase. On December 12th, Kang Enbei and its wholly-owned subsidiary Jinhua Kang Enbei participated in the bidding for the tenth batch of national centralized drug purchase organized by the National Joint Procurement Office for Centralized Drug Purchase and Use. After the bid opening and bid evaluation by the Joint Procurement Office, the company's product Amikacin Sulfate Injection plans to win the bid for this centralized procurement, and the supply provinces have been selected according to the market potential of each province. The successful results will be officially released after being publicized by the Joint Procurement Office. Amikacin sulfate injection is suitable for the treatment of serious infections caused by Pseudomonas aeruginosa, other Pseudomonas, Escherichia coli and other sensitive gram-negative bacilli and Staphylococcus (methicillin-sensitive strains). Compared with the original price, the price of the product to be selected this time has dropped to a certain extent.Musk received an ultimatum from the SEC or faced multiple accusations, and the long-term confrontation between the US SEC and Musk escalated again. On December 12th, local time, Alex spiro, a lawyer of Musk, wrote to Gary Gensler, the outgoing chairman of the SEC, accusing the agency of launching an "ulterior motive action" against Musk, and revealed that the SEC had restarted the investigation of Neuralink, a brain-computer interface company owned by Musk. According to the contents of the letter, the SEC asked Musk to accept the settlement agreement within 48 hours and pay the fine, otherwise he would face "multiple accusations". These allegations are related to Musk's stock investment behavior before the acquisition of Twitter (now "X") in 2022, involving trading time and the legality of information disclosure. It was mentioned in the letter that the accusation originated from an investigation that lasted for several years, and the SEC recently issued a subpoena to Musk's lawyer, asking him to provide testimony. Alex spiro said that he had explicitly refused to cooperate and accused the agency of "political motives". Musk also posted a letter from his lawyer to Gary Gensler on social media, with the text "Gary, how could you do this to me" and a crying emoji. Alex spiro also asked in his letter who was directing the SEC's actions. Alex spiro emphasized that the SEC's "harassment" of Musk and its affiliates for six years has deviated from the original intention of seeking the truth and become an improper pressure. At present, the SEC has not commented on this. In addition, the letter said that the SEC also restarted the investigation of Neuralink, a brain-computer interface company owned by Musk. This autumn, the animal protection organization "Committee of Responsible Medical Doctors" and four US congressmen asked the SEC to investigate Neuralink, accusing it of securities fraud through misleading propaganda. (Securities Times)Market News: US Secretary of State Blinken met with Iraqi Prime Minister in Baghdad to discuss the Syrian issue.

Sources: Russia has suspended grain exports to Syria. Russian and Syrian sources said on Friday that Russia's wheat supply to Syria has been suspended due to the uncertainty of the new Syrian government and the delay in payment.General Administration of Financial Supervision: Help boost consumer support and expand bulk consumption, service consumption and new consumption. The Party Committee of the State Financial Supervision and Administration held a meeting to convey the spirit of studying the Central Economic Work Conference. The meeting requested that the real economy should be better served to help boost consumption and support the expansion of bulk consumption, service consumption and new consumption. Strengthen the financing guarantee for investment and effectively serve the "double" and "two new". Expand the pilot of equity investment of financial asset investment companies in an orderly manner. Do a solid job in supporting the financing coordination mechanism of small and micro enterprises. Increase financial support for foreign trade enterprises and strengthen export credit insurance and credit services. Actively guide banks and insurance institutions to reduce costs and increase efficiency, broaden capital replenishment channels, and improve their sustainable development capabilities. Promote high-level financial openness with higher standards and greater efforts, and attract more foreign financial institutions and long-term capital to set up businesses in China.COMEX silver fell 2.00% in the day and is now quoted at $30.99 per ounce. COMEX silver fell to $31 per ounce, down 1.97% in the day.